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BIOENERGETICS/MITOCHONDRIAL UNIT

The mitochondrial/bioenergetics core provides services for the comprehensive measurement of mitochondrial function and cellular bioenergetics.  The Core, located on the 12th floor of the Biomedical Science Tower, is equipped with two Seahorse XF Bioanalyzers (96 and 24 wells), traditional respirometers, and plate readers , spectrophotometers and microscopes dedicated to the assessment of mitochondrial function by multiple techniques.  The centralization of this core allows the measurement of cellular oxygen consumption, fatty acid oxidation and glycolytic rates, individual mitochondrial enzymatic activities and expression as well as mitochondrial reactive oxygen species and apoptotic signaling.  These measurements can be made in a host of biological samples including isolated mitochondria, cultured/primary cells, tissue and blood cells.

Sruti Shiva, PhD

SRUTI SHIVA, PhD
Director



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