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Vascular Medicine Institute

University of Pittsburgh

Publications utilizing the VMI Free Radical and ROS Core Facility

Rodriguez AI, Gangopadhyay A, Kelley EE, Pagano PJ, Zuckerbraun BS, Bauer PM. (2009). HO-1 and CO Decrease Platelet-Derived Growth Factor-Induced Vascular Smooth Muscle Cell Migration Via Inhibition of Nox1. Arterioscler Thromb Vasc Biol. 30(1):98-104. PMID:19875720.

Kelley EE, Khoo NKH, Hundley NJ, Malik UZ, Freeman BA, Tarpey MM. (2010). Hydrogen peroxide is the major oxidant product of xanthine oxidase. Free Rad. Biol. Med. 48(4):493-8. PMID: 19941951.

Xiao D, Powolny AA, Moura MB, Kelley EE, Bommareddy A, Kim SH, Hahm ER, Normolle D, Van Houten B, Singh SV. (2010). Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells. J Biol Chem. 285:26558-69. PMID: 20571029.

Alef W, Vallabhaneni R, Carchman E, Morris S, Shiva S, Wang Y, Kelley EE, Tarpey MM, Gladwin M, Tzeng E, Zuckerbraun B. (2011). Nitrite-Generated Nitric Oxide Circumvents Dysregulated Arginine/Nitric Oxide Synthase Signaling To Protect Against Intimal Hyperplasia. Journal of Clinical Investigation. 121(4):1646-56.  PMID: 21436585.

Csányi G, Cifuentes-Pagano E, Egaña L, Al Ghouleh I, Lopes LR, Kelley EE, Pagano PJ. (2011). Nox2 B-loop peptide, Nox2ds, specifically inhibits Nox2 oxidase. Free Rad Biol. Med., 51(6):1116-25.  PMID: 21586323.

Manni ML, Tomai LP, Norris CL, Thomas LM, Kelley EE, Salter RD, Crapo JD, Chang LY, Freeman BA, Watkins SC, Pignellie JD, Oury, TD. (2011). Extracellular Superoxide Dismutase Attenuates Bacterial Pneumonia by Promoting Phagocytosis. American Journal of Pathology. 178:2752-9.  PMID: 21641397.

Malik UZ, Hundley NJ, Radi R, Freeman BA, Tarpey MM, Kelley EE. (2011). Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production. Free Rad. Biol. Med. 51(1):179-84, 2011.  PMID: 21554948.

Donadee C, Raat NHJ, Tejero J, Lee JS, Kelley EE, Zhao X, Liu C, Reynolds H, Azarov I, Frizzell S, Meyer EM, Donnenberg AD, Qu L, Triulzi D, Kim-Shapiro DB, Gladwin MT. (2011). Nitric oxide scavenging by red cell microparticles and cell free hemoglobin as a mechanism for the red cell storage lesion. Circulation, 124(4):465-76, 2011.  PMID: 21747051.

Al Ghouleh I, Khoo NK, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, Barchowsky A, Nauseef WM, Kelley EE, Bauer PM, Darley-Usmar V, Shiva S, Cifuentes-Pagano E, Freeman BA, Gladwin MT, Pagano PJ. (2011). Oxidases and Peroxidases in Cardiovascular and Lung Disease: New Concepts in Reactive Oxygen Species Signaling. Free Rad. Biol. Med., 51(7):1271-88. PMID: 21722728.

Hahm ER, Barbi de Moura M, Kelley EE, Shiva S, Van Houten B, Singh SV. (2011). Withaferin A-induced apoptosis in human breast cancer cells is mediated by ROS-dependent activation of Bak., PLoS ONE, 6(8):e23354. PMID: 21853114.

Bernard ME, Kim H, Rwigema JC, Epperly MW, Kelley EE, Murdoch GH, Dixon T, Wang H, Greenberger JS. (2011). Role of the esophageal vagus neural pathway in ionizing radiation induced seizures in nitric oxide synthase-1 homologous recombinant negative (NOS1-/-) mice. In Vivo. 25(6):861-9. PMID: 22021678.