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Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

ALL | JOURNAL CLUB | RESEARCH CONFERENCE | RESEARCH-IN-PROGRESS | SICKLE CELL MTG | SPECIAL SEMINARS


Journal Club

VMI Journal Club is held every other week during the academic year on MONDAYS at 3:30pm in BST 1295.

In this meeting, VMI postdoctoral associates and fellows present recent journal articles for critical analysis and discussion.  Articles must be current, and are expected to meet the highest scientific standards of study design and impact.  Participants are strongly encouraged to select papers relevant to their ongoing projects or broadly related to themes in their respective laboratories.

For more information about this conference, please contact Dr. Iain Scott.
For scheduling, please contact Katie Nauman.

2017

PRESENTER

Sept 11

Sathish Vasamsetti, PhD
(Dutta Lab)

Muller PA, Koscsó B, Rajani GM, Stevanovic K, Berres ML, Hashimoto D, Mortha A, Leboeuf M, Li XM, Mucida D, Stanley ER, Dahan S, Margolis KG, Gershon MD, Merad M, Bogunovic M. Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell. 2014 Jul 17;158(2):300-13. Erratum in: Cell. 2014 Aug 28;158(5):1210. PMID: 25036630 PMCID: PMC4149228

Sept 25

Janet Manning, PhD
(Scott Lab)

Liu W, Ruiz-Velasco A, Wang S, Khan S, Zi M, Jungmann A, Dolores Camacho-Muñoz M, Guo J, Du G, Xie L, Oceandy D, Nicolaou A, Galli G, Müller OJ, Cartwright EJ, Ji Y, Wang X. Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling. Nat Commun. 2017 Sep 8;8(1):494. doi: 10.1038/s41467-017-00664-8. PMID: 28887535; PMCID: PMC5591279.

Oct 9

Andrea Braganza, PhD
(Shiva Lab)

Geng Y, Zhou Y, Wu S, Hu Y, Lin K, Wang Y, Zheng Z, Wu W. Sulforaphane Induced Apoptosis via Promotion of Mitochondrial Fusion and ERK1/2-Mediated 26S Proteasome Degradation of Novel Pro-survival Bim and Upregulation of Bax in Human Non-Small Cell Lung Cancer Cells. J Cancer. 2017 Aug 2;8(13):2456-2470. eCollection 2017. PMID: 28900483; PMCID: PMC5595075.

Oct 23

Elizabeth Rochon, PhD
(Gladwin Lab)

Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, Makita T, Lusis AJ, Kumar SR, Sucov HM. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nat Genet. 2017 Sep;49(9):1346-1353. doi: 10.1038/ng.3929. Epub 2017 Aug 7. PMID: 28783163.

Nov 6

Dharendra Thapa, PhD
(Scott Lab)

Kwon S, Seok S, Yau P, Li X, Kemper B, Kemper JK. Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. J Biol Chem. 2017 Oct 20;292(42):17312-17323. doi: 10.1074/jbc.M117.778720. Epub 2017 Aug 14. PMID: 28808064.

Nov 20

Chris Reyes
(Shiva Lab)

Chen Z, Liu L, Cheng Q, Li Y, Wu H, Zhang W, Wang Y, Sehgal SA, Siraj S, Wang X, Wang J, Zhu Y, Chen Q. Mitochondrial E3 ligase MARCH5 regulates FUNDC1 to fine-tune hypoxic mitophagy. EMBO Rep. 2017 Mar; 18(3):495-509. doi: 10.15252/embr.201643309. Epub 2017 Jan 19. PMID: 28104734. PMCID: PMC5331199.

Dec 4

Luis Hortells, PhD
(St. Hilaire Lab)

Agapova OA, Fang Y, Sugatani T, Seifert ME, Hruska KA. Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease. Kidney Int. 2016 Jun;89(6):1231-43. doi: 10.1016/j.kint.2016.02.002. Epub 2016 Mar 11. PMID: 27165838. PMCID: PMC4868771.