Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

João L. Cavalcante, MD


joao cavalcante


João L. Cavalcante, MD

Assistant Professor of Medicine,
Division of Cardiology

S-558 Scaife Hall
200 Lothrop Street
Pittsburgh, PA 15213

Phone: 412-648-6598
Email: cavalcantejl@upmc.edu

Assistant: Shelly Ossman
ossmanmr@upmc.edu | 412-648-6598

UPMC Profile



Dr. João L. Cavalcante earned his medical degree from the Federal University of Ceará, Brazil. His training includes residency and chief resident in internal medicine and cardiovascular fellowship at Henry Ford Hospital in Detroit, Michigan. He pursued an advanced cardiovascular imaging training at the Cleveland Clinic where he was appointed chief fellow. There he obtained the highest levels of certification and training (COCATS Level III) in the areas of Interventional and Intraoperative Echocardiography, Cardiovascular CT and Cardiac Magnetic Resonance.

Dr. Cavalcante joined the senior faculty of the University of Pittsburgh Heart & Vascular Institute in September 2012 as Assistant Professor of Medicine. Since then he has been actively involved in the heart team evaluation and echocardiographic guidance of minimally invasive percutaneous procedures. In June/2013, he received by unanimous vote the Edward I. Curtiss Outstanding Teacher Award from the cardiology fellows.

Given his clinical focus and research interests in valvular heart disease,Dr. Cavalcante is the Principal Investigator and Director of the Structural Imaging Core Lab of the multicentric study (CLASS-CMR) investigating the role of multimodality imaging in evaluation of paravalvular leak. In addition, he is the site principal investigator of two other valvular imaging trials (ACRIN 4008, TOPAS III) evaluating the role of Cardiac MRI in patients with severe aortic stenosis and in patients undergoing mitral valve surgery for severe primary mitral regurgitation (MRI-MVS Study). He lectures nationally and internationally, has published over 40 manuscripts, 5 book chapters and has several abstracts presented at national and international meetings.

Education and Training

MD, Federal University of Ceará, Fortaleza, Brazil, 2002

Internal Medicine Residency, Henry Ford Hospital, Detroit, MI, 2006

Chief Medical Residency, Henry Ford Hospital, Detroit, MI, 2007

Cardiovascular Diseases Fellowship, Henry Ford Hospital, Detroit, MI, 2010

Advanced Cardiovascular Imaging, Cleveland Clinic, Cleveland, OH, 2012

Research Interests

Multi-modality Imaging for Valvular Disease

Aortic Stenosis

Diastolic Dysfunction


Cavalcante JL, Simon MA, Chan SY. (2017) Comprehensive Right-Sided Assessment for Transcatheter Aortic Valve Replacement Risk Stratification: Time for a Change (Editorial). J Am Soc Echocardiogr. 30:47-51.

Cavalcante JL, Larose E. (2016) Intravascular MRI for Plaque Characterization: Are We Close to Reality? Curr Cardiol Rep. 18(9):89.

Kwon DH, Kusunose K, Obuchowski NA, Cavalcante JL, Popovic ZB, Thomas JD, Desai MY, Flamm SD, Griffin BP. (2016) Predictors and Prognostic Impact of Progressive Ischemic Mitral Regurgitation in Patients with Advanced Ischemic Cardiomyopathy – A Multi-modality Study. Circ Cardiovasc Imaging. 9(7). pii: e004577.

Little SH, Oh JK, Gillam L, Sengupta PP, Orsinelli DA, Cavalcante JL, Chang JD, Adams DH, Zorn GL 3rd, Pollak AW, Abdelmoneim SS, Reardon MJ, Qiao H, Popma JJ. (2016) Self-Expanding Transcatheter Aortic Valve Replacement Versus Surgical Valve Replacement in Patients at High Risk for Surgery: A Study of Echocardiographic Change and Risk Prediction. Circ Cardiovasc Interv. 9(6). pii: e003426. doi: 10.1161/CIRCINTERVENTIONS.115.003426.

Dauerman HL, Reardon MJ, Popma JJ, Little SH, Cavalcante JL, Adams DH, Kleiman NS, Oh JK. (2016) Early Recovery of Left Ventricular Systolic Function After CoreValve Transcatheter Aortic Valve Replacement. Circ Cardiovasc Interv. 9(6). pii: e003425. doi: 10.1161/CIRCINTERVENTIONS.115.003425

Cavalcante JL, Rijal S, Althouse AD, Delgado-Montero A, Katz WE, Schindler JT, Crock F, Harinstein ME, Navid F, Gleason TG, Lee JS. (2016) Right Ventricular Function and Prognosis in Patients with Low-Flow, Low-Gradient Severe Aortic Stenosis. J Am Soc Echocardiogr. 29(4):325-33.

Cavalcante JL, Lalude OO, Schoenhagen P, Lerakis S. (2016) Cardiovascular Magnetic Resonance Imaging for Structural and Valvular Heart Disease Interventions. JACC Cardiovasc Interv. 9(5):399-425.

Vest AR, Patel P, Schauer PR, Satava ME, Cavalcante JL, Brethauer S, Young JB. (2016) Clinical and Echocardiographic Outcomes After Bariatric Surgery in Obese Patients With Left Ventricular Systolic Dysfunction. Circ Heart Fail. 9(3). pii: e002260. doi: 10.1161/CIRCHEARTFAILURE.115.002260.

Cavalcante JL. (2016) Watchful waiting in aortic stenosis: are we ready for individualizing the risk assessment? Eur Heart J. 37(8):724-6 (Editorial).

Cavalcante JL, Marek J, Sheppard R, Starling RC, Mather PJ, Alexis JD, Narula J, McNamara DM, Gorcsan  J 3rd. (2016) Diastolic function improvement is associated with favourable outcomes in patients with acute non-ischaemic cardiomyopathy: insights from the multicenter IMAC-2 trial. Eur Heart J Cardiovasc Imaging. 17(9):1027-35.

Badhwar V, Smith AJ, Cavalcante JL. (2016) Pathoanatomic Approach to the Management of Mitral Regurgitation. Trends Cardiovasc Med. 26(2):126-34.

Cavalcante JL, Marwick TH, Hachamovitch R, Popovic ZB, Aldweib N, Starling RC, Desai MY, Flamm SD, Kwon DH. (2014) Is there a role for diastolic function assessment in era of delayed enhancement cardiac magnetic resonance imaging? A multimodality imaging study in patients with advanced ischemic cardiomyopathy. Am Heart J. 168(2):220-228.

Onishi T, Saha SK, Ludwig DR, Onishi T, Marek JJ, Cavalcante JL, Schelbert EB, Schwartzman D, Gorcsan J 3rd. (2013) Feature tracking measurement of dyssynchrony from cardiovascular magnetic resonance cine acquisitions: comparison with echocardiographic speckle tracking. J Cardiovasc Magn Reson. 15(1):95.

Cavalcante JL, Schoenhagen P. (2013) Role of cross-sectional imaging for structural heart disease interventions. Cardiol Clin. 31(3):467-78.

Cavalcante JL, Tamarappoo BK, Hachamovitch RH, Kwon DH, Alraies MC, Halliburton S, Schoenhagen P, Dey D, Berman DS, Marwick TH. (2012) Association of Epicardial Fat, Hypertension, Subclinical Coronary Artery Disease and Metabolic Syndrome With Left Ventricular Diastolic Dysfunction. Am J Cardiol. 110(12):1793-8.

Cavalcante JL, Rodriguez LL, Kapadia S, Tuzcu EM, Stewart WJ. (2012) Role of echocardiography in percutaneous mitral valve interventions. JACC Cardiovasc Imaging. 5(7):733-46.

Teaching Activities


Invited Faculty for the 2016 Transcatheter Therapies (TCT) Scientific Sessions


Invited International Faculty to the Wuhan Union Hospital International Forum on Ultrasound in Medicine


Invited International Faculty to EuroEcho Imaging 2016 Scientific Sessions


Invited Faculty Member for the American Society of Echocardiography 2016 Scientific Sessions


Invited Faculty Member (Moderator) for the American Heart Association 2016 Scientific Sessions


Invited International Faculty for the 6th Brazilian Congress of Cardiovascular Imaging

Other Scholarly Activities