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VMI
 


Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Cynthia St Hilaire, PhD

 

Cindy St Hilaire

 

Cynthia St Hilaire, PhD

Assistant Professor of Medicine,
Division of Cardiology

1744.1 BST
200 Lothrop Street
Pittsburgh, PA 15261

Phone: 412-648-9441
Fax: 412-624-6161
Email: sthilaire@pitt.edu

Assistant: Diane Margaria
Phone: 412-383-6030
Email: margariad@upmc.edu

  @StHilaireLab

St Hilaire Lab

   

Education

BS - Molecular Genetics
University of Vermont, 2001

PhD - Biochemistry, Program in Cell & Molecular Biology
Boston University School of Medicine, 2008

Postdoctoral Fellow - Vascular Biology
National Heart, Lung, and Blood Institute, 2015


St. Hilaire Laboratory Website

www.sthilairelab.pitt.edu

Publications

St Hilaire C, Ziegler SG, Markello TC, Brusco A, Groden C, Gill F, Carlson-Donohoe H, Lederman RJ, Chen MY, Yang D, Siegenthaler MP, Arduino C, Mancini C, Freudenthal B, Stanescu HC, Zdebik AA, Chaganti RK, Nussbaum RL, Kleta R, Gahl WA, Boehm M. NT5E mutations and arterial calcifications. N Engl J Med. 2011 Feb 3;364(5):432-42. PubMed PMID: 21288095; PubMed Central PMCID: PMC3049958.

Markello TC, Pak LK, St Hilaire C, Dorward H, Ziegler SG, Chen MY, Chaganti K, Nussbaum RL, Boehm M, Gahl WA. Vascular pathology of medial arterial calcifications in NT5E deficiency: Implications for the role of adenosine in pseudoxanthoma elasticum. Mol Genet Metab. 2011 May;103:44-50. PMID 21371928.

Cooley BC, Nevado J, Mellad J, Yang D, St Hilaire C, Negro A, Fang F, Chen G, San H, Walts AD, Schwartzbeck RL, Taylor B, Lanzer JD, Wragg A, Elagha A, Beltran LE, Berry C, Feil R, Virmani R, Ladich E, Kovacic JC, Boehm M. TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling. Sci Transl Med. 2014 Mar 12;6(227):227ra34. PubMed PMID: 24622514; PubMed Central PMCID: PMC4181409.

Liu Y, Jesus AA, Marrero B, Yang D, Ramsey SE, Montealegre Sanchez GA, Tenbrock K, Wittkowski H, Jones OY, Kuehn HS, Lee CC, DiMattia MA, Cowen EW, Gonzalez B, Palmer I, DiGiovanna JJ, Biancotto A, Kim H, Tsai WL, Trier AM, Huang Y, Stone DL, Hill S, Kim HJ, St Hilaire C, Gurprasad S, Plass N, Chapelle D, Horkayne-Szakaly I, Foell D, Barysenka A, Candotti F, Holland SM, Hughes JD, Mehmet H, Issekutz AC, Raffeld M, McElwee J, Fontana JR, Minniti CP, Moir S, Kastner DL, Gadina M, Steven AC, Wingfield PT, Brooks SR, Rosenzweig SD, Fleisher TA, Deng Z, Boehm M, Paller AS, Goldbach-Mansky R. Activated STING in a vascular and pulmonary syndrome. N Engl J Med. 2014 Aug 7;371(6):507-18. PubMed PMID: 25029335; PubMed Central PMCID: PMC4174543.

P. Lanzer, M. Boehm, V. Sorribas, M. Thiriet, J. Janzen, T. Zeller, C. St. Hilaire, C. Shanahan. Medial vascular calcification revisited: review and perspectives. Eur Heart J. 2014 Jun 14;35(23):1515-1525. PMID 24740885.

Boehm M, St. Hilaire C. Vascular Genetics. In: Lanzer P. (Ed.) PanVascular Medicine, 2nd edition, vol.x, pp 53-88. Springer Heidelberg New York Dordrecht London, 2015. DOI: 10.1007/978-3-642-37393-0_4-1