Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Benign Hematology Clinical and Research Faculty and Programs

Vascular Biology, Platelets, and Hemostasis

	MATTHEW NEAL, MD Hemostasis, Inflammation, Thrombosis, Trauma, and Transfusion Surgical Outcomes (HIT3S) Research Group		MARGARET RAGNI, MD, MPH Novel therapies for hemophilia and Von Willebrand Disease (VWD)
	MARK GLADWIN, MD Donor genetic variations can affect hemolytic propensity and RBC storage recovery and function		YINGZE ZHANG, PhD Genetic Control of Thrombospondin Transcription and Vasculopathy in Sickle Cell Disease
	ENRICO NOVELLI, MD, MS Novel Biomarkers in Sickle Cell Anemia		SRUTI SHIVA, PhD Mitochondria, Platelets, and Heme
	KARIN POTOKA, MD Soluble guanylyl cyclase stimulation as a potential treatment in sickle cell disease

Iron, Heme, and Globins

	GRANT BULLOCK, MD, PhD Aconitase: an iron-sensing regulator of mitochondrial oxidative metabolism and erythropoiesis		JOSEPH KISS, MD Impact of Iron Status and Anemia in Blood Donors... Does it Matter for RBC Transfusion Therapy
	PAOLA CORTI, PhD Investigating the function of zebrafish globins in development and heart generation		ADAM STRAUB, PhD Mechanisms of heme redox regulation
	TAMIR KANIAS, PhD Red Blood Cells		AISHA WALKER, PhD Cellular and Molecular Mediators of Fetal Hemoglobin Expression: The Land Before Blood Cells

TLR4 and the Immune System

	LISA BORGHESI, PhD Role of Toll-like receptors in hematopoiesis		GREGORY KATO, MD Heme, Inflammasome, and Sickle Cell Disease
	PARTHA DUTTA, DVM, PhD Hematopoiesis in Cardiovascular Disease		SOLOMON OFORI-ACQUAH, PhD Extracellular heme: a prototypical erythroid DAMP molecule and effector pathogen of sickle crisis
	CHERYL HILLERY, MD HMGB1 and TLR4 in Sickle Cell Disease		PRITHU SUNDD, PhD Role of platelet TLR4, NLRP3-inflammasome and extracellular vesicles in sickle cell disease

Something Old, Something New

	FRANKLIN BONTEMPO, MD HCWP		LAURA DE CASTRO, MD, MHSc Translation from Biology to Clinical Trials in Sickle Cell Disease
	CHARLES JONASSAINT, PhD Using Mobile Technology to Bridge Gaps in Sickle Cell Disease Care		DARRELL TRIULZI, MD Anti-fibrinolytic Agents in the Management of Thrombocytopenia