UPMC HEART AND VASCULAR INSTITUTE | UNIVERSITY OF PITTSBURGH | FIND PEOPLE
VMI
 


Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Chan Laboratory


Contact

Lab phone: 412-648-2094

Lab address: 1702 Biomedical Science Tower (Starzl BST), 200 Lothrop Street, Pittsburgh, PA 15261


Research

Dr Chan's lab studies the molecular mechanisms of pulmonary vascular disease and pulmonary hypertension (PH). Ongoing projects include: 1) Defining the network biology of non-coding RNAs in pulmonary hypertension, 2) Studying the molecular regulation of mitochondrial metabolism by microRNAs, and 3) Defining the regulation of circulating microRNAs in hypoxia and exercise.


People

PRINCIPAL INVESTIGATOR
 

STEPHEN Y. CHAN, MD, PhD

Associate Professor of Medicine, Division of Cardiology

chansy@pitt.edu | 412-383-6030

 

POSTDOCS / FELLOWS
 

VINNY NEGI, PhD

Postdoctoral Associate

Vinny recently graduated from Institute of Genomics and Integrative Biology (IGIB), Delhi, India with a doctrate degree. In free time, Vinny likes listening to music, dancing and watching movies.

negiv@pitt.edu | 412-383-1276

     
 

JOO HEUNG YOON, MD

Pulmonary Fellow

yoonjh@upmc.edu | 412-383-1273

     
 

QIUJUN YU, MD, PhD

Postdoctoral Associate

yuqiu@pitt.edu | 412-383-1270

 

GRADUATE STUDENTS
 

ANNA RAMOS

Medical Student

Anna is a first year medical student at the University of Pittsburgh School of Medicine. She is interested in the response of circulating miRNAs to aerobic exercise.
If not in the lab (or studying for medical school), she is probably rehearsing with the University of Pittsburgh School of Health Sciences a cappella group PalPITTations, training for another half-marathon, or searching for the best dessert in the city.

Ramos.Anna@medstudent.pitt.edu | 412-383-1270

 

RESEARCH STAFF
 

MIRANDA TAI, MS

Laboratory Technician

Miranda recently graduated from Carnegie Mellon University with a master degree in Biomedical Engineering. She is interested in the roles and functions of microRNA and long-noncoding-RNA in pulmonary hypertension.
In her spare time, Miranda enjoys art, music, playing badminton, kayaking, and exploring new places as well as trying out new (yummy) food!

taiy@upmc.edu | 412-383-1270

     
 

YING TANG

Research Specialist IV, Senior Lab Manager

Ying has extensive experience in the development of viral vectors and the application of stem cells for gene and cell therapy, especially for musculoskeletal disease and injury. She has played a major role in the following projects: 1) recombinant adeno-associated viral (AAV) vector-based gene therapy for the treatment of Duchenne muscular dystrophy (DMD); 2) bone regeneration including the use of gene-enhance human mesenchymal stem cell with biomaterial scaffolds; 3) the development of techniques in small animal experiments and imaging.
Her research is focused on the field of gene transfer and stem cell modification utilizing AAV, lentivirus and retrovirus. She is currently investigating: 1) the response of pulmonary and peripheral blood vessels to hypoxic and ischemic injury; 2) strategies for the treatment of pulmonary hypertension (PH).
In these projects, small animals, such as transgenic and double-knock out mice, are bred, genotyped and treated for pulmonary and peripheral blood vessel related diseases. Imaging techniques frequently used in these animal experiments include micro-CT for bone imaging.  Imaging techniques employed in cell-based experiments include dot blot, western blot and other immunostaining procedures.

yit3@pitt.edu | 412-648-2094

   

 

 

JINGSI ZHAO, MS

Laboratory Technician

Jingsi graduated from Nanjing University in China with a B.S. degree in Biological Sciences, and then gained the M.S. degree in Biomedical Engineering from Carnegie Mellon University. As a research lab technician, Jingsi is working to be responsible for maintaining the laboratory animal colony and performing multiple rodent manipulation experiments which are involved in several projects in the lab. She is excited to work here because she wants to apply her biological knowledge and laboratory skills to studying the function and regulation of microRNA in pulmonary hypertension, and also gain more research experience. When not doing science, Jingsi enjoys watching movies and listening to music.

zhaoj5@upmc.edu | 412-648-2094

 
UNDERGRADUATES
 

LEONARD ESTEPHAN

Undergraduate Researcher

Leonard is an undergraduate student studying biological sciences at the University of Pittsburgh. Post-graduation, he plans on attending medical school and becoming a physician. In his free time his favorite things to do are listen to music, play sports, explore Pittsburgh, and watch movies with his friends.

lee22@pitt.edu | 412-648-2094

     
 

JOSEPH CHEN

Undergraduate Researcher

Joseph is a sophomore at the University of Pittsburgh and is a Biology major with the goal of becoming a physician. Joseph is eager to broaden his laboratory experiences and work in translational research. When he is not immersed in his studies, he enjoys staying fit, playing recreational sports such as basketball and tennis, and exploring Pittsburgh with his friends.

joseph.chen.139@pitt.edu | 412-648-2094