UPMC HEART AND VASCULAR INSTITUTE | UNIVERSITY OF PITTSBURGH | FIND PEOPLE
VMI
 


Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Pagano Laboratory

Pagano Lab Sept 2013

Contact

Lab phone: 412-648-2610

Lab address: E1200 Biomedical Science Tower (Starzl BST), 200 Lothrop Street, Pittsburgh, PA 15261


Available Position(s): POSTDOCTORAL ASSOCIATE


Research

The overall goal of our laboratory is to investigate the role of NADPH oxidase in normal cellular function as well as under a variety of pathophysiological conditions. We are currently developing isoform-specific inhibitors to delineate the contribution of specific NADPH oxidase isoforms in elevated reactive oxygen species (ROS) production in various cardiovascular diseases (CVDs). We are also employing conventional and cutting-edge technologies such as immuno-spin trapping, mass spectroscopy and proteomics to investigate the mechanisms mediating the effect of adventitia-derived hydrogen peroxide (H2O2) as a paracrine mediator of vascular dysfunction in CVD.

See also: Free Radical and Reative Oxygen Species (ROS) Core Facility

 

People

PRINCIPAL INVESTIGATOR
  Patrick Pagano

PATRICK J. PAGANO, PhD

Professor and Vice-Chair, Graduate Education
Department of Pharmacology and Chemical Biology
Program Director, Molecular Pharmacology Graduate Program

pagano@pitt.edu | 412-383-6505

 

FACULTY
  Eugenia Cifuentes

M. EUGENIA CIFUENTES-PAGANO, PhD

Instructor, Department of Pharmacology and Chemical Biology

Developing and validating isoform-specific inhibitors of NADPH oxidase

mec110@pitt.edu | 412-648-2610

 

POSTDOCS / FELLOWS
 

YAO LI, PhD

Postdoctoral Associate

yal102@pitt.edu | 412-648-2610

     
 

DANIEL SIMOES de JESUS, PhD

Postdoctoral Associate

das270@pitt.edu | 412-648-2610

     
  Sangha Sahoo

SANGHAMITRA SAHOO, PhD

Postdoctoral Associate

Dr. Sahoo is interested in evaluating the role of micro-RNAs (miRs) in regulating Nox-dependent ROS generation and in regulating pulmonary vascular remodeling in the settings of Pulmonary Arterial Hypertension.

sas279@pitt.edu | 412-648-2610

 

GRADUATE STUDENTS
 

ANASTASIA GORELOVA

Graduate Student, Interdisciplinary Biomedical Sciences Program

ang123@pitt.edu | 412-648-2610

 

UNDERGRADUATE STUDENTS
 

LATIA TUCKER

Student Research Assistant

tuckerl@pitt.edu| 412-648-2610

     
 

JAMES KEARNEY

Student Research Assistant

412-648-2610



Pagano Lab 2016


Previous lab members:

  1. Arash Kiarash, M.D. Postdoctoral Research Fellow, 1998-2001; Current status: Practicing Internist.
  2. Nagamasa Ogasawara, M.D. Postdoctoral Research Fellow, 1998- 2000. Current status; Practicing Internist, Japan.
  3. Justin C. Clark, B.S. Graduate Student in Basic Medical Sciences- Boston University, 1996-1998. Current Status: Practicing Physician.
  4. Federico Rey, Ph.D. Postdoctoral Research Fellow, 1999-2001, went on to do a Ph.D. in microbiology at the University of Iowa; Current Position: Postdoctoral Fellow at Washington University in microbiology and cell signaling.
  5. Gary Jacobson, M.D. Vascular Surgery Research Fellow, 2000-2001. Current position: Private practice, Surgery.
  6. Hector Dourron, M.D. Vascular Surgery Research Fellow, 2001-2002. Current position: Private practice, Surgery; Clinical Research.
  7.  Jianhua Liu, M.D., Postdoctoral Research Fellow, 2001-2002. Current position: Research Associate, Wayne State University.
  8. Mitchell Weaver, M.D., Vascular Surgery Research Fellow, 2002-2003. Current Position: Senior Staff Surgeon, Academic position in Vascular Surgery, Henry Ford Hospital.
  9. James. L. Park, Ph.D., Research Instructor, 2003-2005. Current Position: Staff Scientist, University of Michigan Medical Center.
  10. Noelia Ardanaz-Martinez, Ph.D., Postdoctoral Research Fellow, 2003-2006. Current Position: Pharmaceutical Research Scientist, Barcelona, Spain.
  11. Mounir Haurani, M.D., Surgery Postdoctoral Research Fellow, 2005–2007. Current Position: Vascular surgery research fellowship, Massachusetts General Hospital, Boston, MA.
  12. Michael Best, BS, Summer Research Intern, University of Michigan, 2006. Current Position: accepted, graduate program, Johns Hopkins School of Public Health.
  13. Thomas Cascino, Undergraduate Research Intern, University of Michigan, 2007. Current Position: medical student, Loyal University  
  14. Kristy Kelel, Master’s Degree Candidate, Biomedical Sciences Program, Wayne State University, 2007. Current Position: medical student, Wayne State University.
  15. Joseph Fiorillo, M.S.,; Graduate Student in Basic Medical Sciences-BostonUniversity (Dissertation advisor), 1994-1995.
  16. John P. Hezel; Bedford High School Science Program (Project Advisor), 1995.
  17. Mark C. Griswold, B.S., Boston University, 1993-1996.
  18. Sohang Chatterjee, M.S., Henry Ford Hospital, 1998.
  19. Juan Zhang, M.D. Research Fellow, 2003-2004.
  20. Kyle Jackson, Summer Medical Intern in Research, Wayne State University, 2006.
  21. Abeba Berhane, Summer Medical Intern in Research, University of Michigan, 2006.
  22. Siddharth Siva, Undergraduate Research Intern, Yale University, 2007.
  23. Yanlin Lu, M.D., Postdoctoral Research Fellow, 2007 – 2008.
  24. Claudia Castro, Ph.D., Fulbright Scholar, 2010. Current Position: Docente Facultad de Ciencias Medicas, U. Nacional de Cuyo, Argentina
  25. Judy Lee, Student Research Assistant, -2010
  26. Loreto Egaña, Health Sciences Fellow, -2011
  27. Andres Rodriguez, PhD, Postdoctoral Fellow 2007-2013. Current Position: Investigator at Instituto do Coraçao / FMUSP, Brazil, and U. de Bio Bio, Chile
  28. Jefferson Heinrich Amaral, PhD, Visiting Scholar, University of São Paulo, Brazil, -2014
  29. Daniel Ranayhossaini, PhD, Graduate Student, 2010-2014. Postdoctoral Associate, 2014. Current Position: Laboratory Head at Bayer HealthCare, Germany
  30. Gabor Csanyi, PhD, Postdoctoral Fellow 2007-2013, Research Instructor 2013-2015. Current Position: Assistant Professor, Georgia Regents University
  31. Daniel Meijles, PhD, International Postdoctoral Research Scholar 2013-2015.