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VMI
 


Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Sathish Babu Vasamsetti, PhD

 

Gladwin

 

Sathish Vasamsetti, PhD

Postdoctoral Associate, Dutta Lab

1720 BST
200 Lothrop Street
Pittsburgh, PA 15261

Phone: 412-624-4059
Email: sathishv@pitt.edu


   

Bio

Dr. Vasamsetti received his masters degree in microbiology in 2008 from Acharya Nagarjuna University, India. He was awarded with CSIR junior research fellowship in 2009 to study the mechanisms of monocyte to macrophage differentiation along with the identification of key cellular targets during this process in cardiovascular disorders in Dr. Kotamraju S lab at CSIR-IICT (India).  In 2015, he was awarded with PhD in Biochemistry from Academic Council of Scientific and Industrial Research (AcSIR), India. In 2016, he joined Dr. Partha Dutta’s lab to investigate the differential regulation of tissue resident and monocyte-derived macrophages in myocardial infarction-induced insulin resistance in the Vascular Medicine Institute at the University of Pittsburgh.


Publications

Vasamsetti SB, Karnewar S, Kanugula AK, Kotamraju S.  Metformin inhibits monocyte-to-macrophage differentiation via AMPK mediated inhibition of STAT3 activation: Potential role in atherosclerosisDiabetes 2015; 64:2042-2055.

Gannarapu MR, Vasamsetti SB, Punna N, Kotamraju S, Banda N. Design and synthesis of novel 1-substituted-triazole linked 1,2-benzothiazine 1,1-dioxido propenone derivatives and their evaluation as potent anti-inflammatory agents and inhibitors of monocyte-to-macrophage transformation.  Med Chem Comm 2015:6:1494-1500.

Kanugula AK, Gollavilli PN, Vasamsetti SB, Karnewar S, Gopoju R, Ummanni R, Kotamraju S. Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: Intermediacy of nitric oxide and antioxidant defence mechanisms. FEBS J. Aug;281(16):3719-38.

Sambasiva Rao P, Kurumurthy C, Veeraswamy B, Santhosh Kumar G, Poornachandra Y, Ganesh Kumar C, Vasamsetti SB, Kotamraju S, Narsaiah B. Synthesis of novel 1,2,3-triazole substituted-N-alkyl/aryl nitrone derivatives, their anti-inflammatory and anticancer activity. Eur J Med Chem. 2014 Jun 10; 80:184-91.

Gannarapu MR, Vasamsetti SB, Punna N, Royya NK, Pamulaparthy SR, Nanubolu JB, Kotamraju S, Banda N. Synthesis of novel 1,2-benzothiazine 1,1-dioxide-3-ethanone oxime N-aryl acetamide ether derivatives as potent anti-inflammatory agents and inhibitors of monocyte-to-macrophage transformation. Eur J Med Chem.2014 Mar 21;75:143-50.

Koppireddi S, Komsani JR, Avula S, Pombala S, Vasamsetti S, Kotamraju S, Yadla R. Novel 2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamides as antioxidant and/or anti-inflammatory compounds. Eur J Med Chem. 2013 Aug; 66:305-13.