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October 28, 2020 @ 12:00 pm
Yvette Yien, PhD
University of Delaware
Regulation of mitochondrial iron metabolism in erythroid cells
- Mutation in Human CLPX Elevates Levels of δ- Aminolevulinate Synthase and Protoporphyrin IX to Promote Erythropoietic Protoporphyria
- FAM210B Is an Erythropoietin Target and Regulates Erythroid Heme Synthesis by Controlling Mitochondrial Iron Import and Ferrochelatase Activity
- Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis