Associate Professor of Medicine, Division of Cardiology
Associate Professor of Bioengineering

Research Interests

Dr. Kaufman’s long-standing research interest is to understand the contribution of mtDNA metabolism to disease progression. For 20 years he has been uncovering the fundamental processes that underlie mitochondrial respiratory deficiency with a focus on mtDNA stability and copy number control – processes essential for respiratory function and viability. Dr. Kaufman’s major research goals are 1) to define the biochemical events responsible for the maintenance of mtDNA content, 2) to understand how distinct pathways influence mtDNA maintenance, and 3) to understand mechanisms of mtDNA damage and resistance to damage in the context of disease.

Education and Training

Course in Cell Physiology, Marine Biological Laboratory, 1996
Postdoc, McGill University, 2008

Selected/Representative Publications

For a complete bibliography, click here.