
Office Location
BST E1241
Lab Location
BST E1200-28/29
Email: bkauf@pitt.edu
Phone: 412-383-6031
Assistant:
Erica Carson carsonec@upmc.edu
Brett A. Kaufman, PhD
Associate Professor of Medicine, Division of Cardiology
Associate Professor of Bioengineering
Research Interests
Dr. Kaufman’s long-standing research interest is to understand the contribution of mtDNA metabolism to disease progression. For 20 years he has been uncovering the fundamental processes that underlie mitochondrial respiratory deficiency with a focus on mtDNA stability and copy number control – processes essential for respiratory function and viability. Dr. Kaufman’s major research goals are 1) to define the biochemical events responsible for the maintenance of mtDNA content, 2) to understand how distinct pathways influence mtDNA maintenance, and 3) to understand mechanisms of mtDNA damage and resistance to damage in the context of disease.
Education and Training
Ph.D., University of Texas Southwestern Medical Center at Dallas, 2003
Course in Cell Physiology, Marine Biological Laboratory, 1996
Postdoc, McGill University, 2008
Selected/Representative Publications
For a complete bibliography, click here.