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Cardiovascular Outcomes and Innovation

The UPMC Heart and Vascular Institute’s Center for Cardiovascular Outcomes and Innovation (COIN) supports cardiology and cardiac surgery researchers by providing high-quality data collection, analysis, and interpretation.

What We Do

The experts at the HVI-COIN use proven statistical and mathematical methods to provide a range of research support services, including:

  • Guidance and direction in determining key study components like hypotheses, specific aims, and sample size
  • Database development and maintenance
  • Data collection, analysis, and interpretation
  • Abstract, presentation, and manuscript preparation
Benefits for Researchers

Because our team is specifically dedicated to heart-related projects and comprised of individuals specializing in cardiovascular research, we have a better understanding of HVI research needs than the average statistician. Researchers get high-quality results in timely manner from a team that is invested in their success.

Who We Are

Yisi Wang, MPH | Staff Biostatistician

Yisi Wang received a medical degree in Internal Medicine at Sichaun University, China. After working as a lab research fellow at Weill Cornell Medical College, she pursued a master degree in Public Health in Epidemiology at the University of Pittsburgh. Upon graduation, she worked at the Liver and Cancer Center / Liver Pancreas Institute prior to joining HVI-COIN in October 2018. She works as a staff biostatistician on projects in general cardiology and cardiac surgery, bringing expertise in data analytics and SAS programming.

Floyd W. Thoma | Research Data Manager

Mr. Thoma received his Bachelor’s of Science in Psychology and History and Philosophy of Science from the University of Pittsburgh in 1995.  During his career he has worked on a tremendous breadth of research at UPMC, involving topics such as Motivational Interviewing, Neuropsychological testing, Diabetes, and Cardiology.  Most recently, he worked in the CathPCI registry for 2 years where he implemented measures to catch medication fallouts, post-PCI events, and door-to-balloon times to help to reduce reporting errors.  His chief expertise is in the creation, design, and maintenance of research-quality databases.

Contact Us

To schedule a consultation for research support, call 412-802-6811 or email