Amdahl MB, DeMartino AW, Gladwin MT. Inorganic nitrite bioactivation and role in physiological signaling and therapeutics. Biol Chem. 2019 Dec 18;401(1):201-211.

Amdahl MB, Petersen EE, Bocian K, Kaliszuk SJ, DeMartino AW, Tiwari S, Sparacino-Watkins CE, Corti P, Rose JJ, Gladwin MT, Fago A, Tejero J. The Zebrafish Cytochrome b(5)/Cyto-chrome b(5) Reductase/NADH System Efficiently Reduces Cytoglobins 1 and 2: Conserved Activity of Cytochrome b(5)/Cytochrome b(5) Reductases during Vertebrate Evolution. Biochemistry. 2019 Jul 23;58(29):3212-3223. Epub 2019 Jul 10.

Axelsson Raja A, Shi L, Day SM, Russell M, Zahka K, Lever H, Colan SD, Margossian R, Hall EK, Becker J, Jefferies JL, Patel AR, Choudhury L, Murphy AM, Canter C, Bach R, Taylor M, Mestroni L, Wheeler MT, Benson L, Owens AT, Rossano J, Lin KY, Pahl E, Pereira AC, Bundgaard H, Lewis GD, Vargas JD, Cirino AL, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E, Ho CY. Baseline Characteristics of the VANISH Cohort. Circ Heart Fail. 2019 Dec;12(12):e006231. Epub 2019 Dec 9.

Bennewitz MF, Tutuncuoglu E, Gudapati S, Brzoska T, Watkins SC, Monga SP, Pradhan-Sundd T, Sundd P. P-selectin-deficient mice to study pathophysiology of sickle cell disease. Blood Adv. 2020 Jan 28;4(2):266-273.

Bhagwani AR, Farkas D, Harmon B, Authelet KJ, Cool CD, Kolb M, Goncharova E, Yoder MC, Clauss M, Freishtat R, Farkas L. Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia. Sci Rep. 2020 Jan 24;10(1):1136.

Bourgeois A, Bonnet S, Breuils-Bonnet S, Habbout K, Paradis R, Tremblay E, Lampron MC, Orcholski ME, Potus F, Bertero T, Peterlini T, Chan SY, Norris KA, Paulin R, Provencher S, Boucherat O. Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension. Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1667-1681. Epub 2019 May 16.

Braganza A, Annarapu GK, Shiva S. Blood-based bioenergetics: An emerging translational and clinical tool. Mol Aspects Med. 2020 Feb;71:100835. Epub 2019 Dec 18.

Burki S, Noda K, Philips BJ, Velayutham M, Shiva S, Sanchez PG, Kumar A, D’Cunha J. Impact of triptolide during ex vivo lung perfusion on grafts after transplantation in a rat model. J Thorac Cardiovasc Surg. 2020 Jan 23:S0022-5223(20)30191-4. Online ahead of print.

Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Mor-genstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Sci Adv. 2020 Apr 1;6(14):eaay9572. eCollection 2020 Apr.

Caughey MC, Novelli EM. Editorial commentary: Sickle cell disease: Diagnosing the heart of the matter. Trends Cardiovasc Med. 2020 Feb 28:S1050-1738(20)30033-5. Online ahead of print.

Chung KW, Dhillon P, Huang S, Sheng X, Shrestha R, Qiu C, Kaufman BA, Park J, Pei L, Baur J, Palmer M, Susztak K. Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis. Cell Metab. 2019 Oct 1;30(4):784-799.e5. Epub 2019 Aug 29.

Cole LK, Mejia EM, Sparagna GC, Vandel M, Xiang B, Han X, Dedousis N, Kaufman BA, Dolinsky VW, Hatch GM. Cardiolipin deficiency elevates suscep-tibility to a lipotoxic hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2020 Jul;144:24-34. Epub 2020 May 11.

Culley MK, Perk D, Chan SY. NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in Our Thinking. Am J Respir Cell Mol Biol. 2020 Feb;62(2):136-138.

Cyr A, Chambers L, Waltz PK, Whelan SP, Kohut L, Carchman E, Dyer M, Luciano J, Kautza B, Gomez HD, Otterbein LE, Rosengart MR, Shiva S, Zuckerbraun BS. Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes. Oxid Med Cell Longev. 2019 Oct 24;2019:4745067. eCollec-tion 2019.

Cyr AR, Huckaby LV, Shiva SS, Zuckerbraun BS. Nitric Oxide and Endothelial Dysfunction. Crit Care Clin. 2020 Apr;36(2):307-321.

D’Alessandro A, Fu X, Kanias T, Reisz JA, Culp-Hill R, Guo Y, Gladwin MT, Page G, Kleinman S, Lanteri M, Stone M, Busch MP, Zimring JC; Recipient Epidemiology and Donor Evaluation Study-III (REDS III). Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glu-cose 6-phosphate dehydrogenase levels and activity. Haematologica. 2020 Apr 2:haematol.2020.246603. Online ahead of print.

DeLalio LJ, Hahn S, Katayama PL, Wenner MM, Farquhar WB, Straub AC, Stocker SD. Excessive dietary salt promotes aortic stiffness in murine renovascular hypertension. Am J Physiol Heart Circ Physiol. 2020 May 1;318(5):H1346-H1355. Epub 2020 Apr 17.

DeVallance E, Li Y, Jurczak MJ, Cifuentes-Pagano E, Pagano PJ. The Role of NADPH Oxidases in the Etiology of Obesity and Metabolic Syndrome: Contribution of Individual Isoforms and Cell Biology. Antioxid Redox Sig-nal. 2019 Oct 1;31(10):687-709.

Donnenberg AD, Kanias T, Triulzi DJ, Dennis CJ, Meyer EM, Gladwin M. Improved quantitative detection of biotin-labeled red blood cells by flow cytometry. Transfusion. 2019 Aug;59(8):2691-2698. Epub 2019 Jun 6.

Donnenberg AD, Kanias T, Triulzi DJ, Dennis CJ, Moore LR, Meyer EM, Sinchar D, Kiss JE, Normolle DP, Gladwin MT. Current good manufacturing practices-compliant manufacture and measurement of biotin-labeled red blood cells. Cytotherapy. 2019 Jul;21(7):793-800. Epub 2019 May 14.

Dosunmu-Ogunbi AM, Wood KC, Novelli EM, Straub AC. Decoding the role of SOD2 in sickle cell disease. Blood Adv. 2019 Sep 10;3(17):2679-2687.

Durgin BG, Hahn SA, Schmidt HM, Miller MP, Hafeez N, Mathar I, Freitag D, Sandner P, Straub AC. Loss of smooth muscle CYB5R3 amplifies angiotensin II-induced hypertension by increasing sGC heme oxidation. JCI Insight. 2019 Oct 3;4(19):e129183.

Dyer MR, Alexander W, Hassoune A, Chen Q, Brzoska T, Alvikas J, Liu Y, Haldeman S, Plautz W, Loughran P, Li H, Boone B, Sadovsky Y, Sundd P, Zuckerbraun BS, Neal MD. Platelet-derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice. J Thromb Haemost. 2019 Oct;17(10):1733-1745. Epub 2019 Jul 28.

Farrell AT, Panepinto J, Desai AA, Kassim AA, Lebensburger J, Walters MC, Bauer DE, Blaylark RM, DiMichele DM, Gladwin MT, Green NS, Hassell K, Kato GJ, Klings ES, Kohn DB, Krishnamurti L, Little J, Makani J, Malik P, McGann PT, Minniti C, Morris CR, Odame I, Oneal PA, Setse R, Sharma P, Shenoy S. End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Adv. 2019 Dec 10;3(23):4002-4020.

Gbotosho OT, Ghosh S, Kapetanaki MG, Lin Y, Weidert F, Bullock GC, Ofori-Acquah SF, Kato GJ. Cardiac expression of HMOX1 and PGF in sickle cell mice and haem-treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2). Br J Haematol. 2019 Dec;187(5):666-675. Epub 2019 Aug 6.

Gbotosho OT, Kapetanaki MG, Ross M, Ghosh S, Weidert F, Bullock GC, Watkins S, Ofori-Acquah SF, Kato GJ. Nrf2 deficiency in mice attenuates erythropoietic stress-related macrophage hypercellularity. Exp Hematol. 2020 Apr;84:19-28.e4. Epub 2020 Mar 6.

George MP, Gladwin MT, Graham BB. Exploring New Therapeutic Pathways in Pulmonary Hypertension: Metabolism, Proliferation, and Personalized Medicine. Am J Respir Cell Mol Biol. 2020 May 26. Online ahead of print.

Ghosh S, Flage B, Weidert F, Ofori-Acquah SF. P-selectin plays a role in haem-induced acute lung injury in sickle mice. Br J Haematol. 2019 Jul;186(2):329-333. Epub 2019 Feb 27.

Goncharova EA, Simon MA, Yuan JX. mTORC1 in Pulmonary Arterial Hypertension. At the Crossroads between Vasoconstriction and Vascular Remodeling? Am J Respir Crit Care Med. 2020 May 15;201(10):1177-1179.

Gong Z, Zhang X, Su K, Jiang R, Sun Z, Chen W, Forno E, Goetzman ES, Wang J, Dong HH, Dutta P, Muzumdar R. Deficiency in AIM2 induces inflammation and adipogenesis in white adipose tissue leading to obesity and insulin resistance. Diabetologia. 2019 Dec;62(12):2325-2339. Epub 2019 Sep 11.

Gouraud E, Charrin E, Dubé JJ, Ofori-Acquah SF, Martin C, Skinner S, Chatel B, Boreau A, Messonnier LA, Connes P, Pialoux V, Hautier C, Faes C. Effects of Individualized Treadmill Endurance Training on Oxidative Stress in Skeletal Muscles of Transgenic Sickle Mice. Oxid Med Cell Longev. 2019 Jul 24;2019:3765643. eCollection 2019.

Hansmann G, Calvier L, Risbano MG, Chan SY. Activation of the Metabolic Master Regulator PPARβ: A Potential PIOneering Therapy for Pulmonary Arterial Hypertension. Am J Respir Cell Mol Biol. 2020 Feb;62(2):143-156.

Hill BG, Shiva S, Ballinger S, Zhang J, Darley-Usmar VM. Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine. Biol Chem. 2019 Dec 18;401(1):3-29.

Hoyer FF, Naxerova K, Schloss MJ, Hulsmans M, Nair AV, Dutta P, Calcagno DM, Herisson F, Anzai A, Sun Y, Wojtkiewicz G, Rohde D, Frodermann V, Vandoorne K, Courties G, Iwamoto Y, Garris CS, Williams DL, Breton S, Brown D, Whalen M, Libby P, Pittet MJ, King KR, Weissleder R, Swirski FK, Nahrendorf M. Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. 2019 Nov 19;51(5):899-914.e7. Epub 2019 Nov 12.

Hoyer FF, Zhang X, Coppin E, Vasamsetti SB, Modugu G, Schloss MJ, Rohde D, McAlpine CS, Iwamoto Y, Libby P, Naxerova K, Swirski FK, Dutta P, Nahrendorf M. Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes Mellitus. Circulation. 2020 Jul 21;142(3):244-258. Epub 2020 Apr 22.

Jin K, Ma Y, Manrique-Caballero CL, Li H, Emlet DR, Li S, Baty CJ, Wen X, Kim-Campbell N, Frank A, Menchikova EV, Pastor-Soler NM, Hallows KR, Jackson EK, Shiva S, Pinsky MR, Zuckerbraun BS, Kellum JA, Gómez H. Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness. FASEB J. 2020 May;34(5):7036-7057. Epub 2020 Apr 4.

Jin S, Zeng X, Fang J, Lin J, Chan SY, Erzurum SC, Cheng F. A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications. NPJ Syst Biol Appl. 2019 Nov 13;5:41. eCollection 2019.

Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ. Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus. JCI Insight. 2020 Jan 16;5(1):e128578.

Kapetanaki MG, Gbotosho OT, Sharma D, Weidert F, Ofori-Acquah SF, Kato GJ. Free heme regulates placenta growth factor through NRF2-antioxidant response signaling. Free Radic Biol Med. 2019 Nov 1;143:300-308. Epub 2019 Aug 10.

Kim EJ, Fox S, Moretti ME, Turner M, Girard TD, Chan SY. Motivations and Barriers Associated With Physician Volunteerism for an International Telemedicine Organization. Front Public Health. 2019 Aug 13;7:224. eCollection 2019.

Kim SH, Hahm ER, Singh KB, Shiva S, Stewart-Ornstein J, Singh SV. RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cells. Carcinogenesis. 2020 Jul 10;41(6):778-789.

Koczo A, Marino A, Jeyabalan A, Elkayam U, Cooper LT, Fett J, Briller J, Hsich E, Blauwet L, McTiernan C, Morel PA, Hanley-Yanez K, McNamara DM; IPAC Investigators. Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy. JACC Basic Transl Sci. 2019 Jun 24;4(3):291-300. eCollection 2019 Jun.

Kolesar JE, Kaufman BA. Using Two-Dimensional Intact Mitochondrial DNA (mtDNA) Agarose Gel Electrophoresis (2D-IMAGE) to Detect Changes in Topology Associated with Mitochondrial Replication, Transcription, and Damage. Methods Mol Biol. 2020;2119:25-42.

Kopechek JA, McTiernan CF, Chen X, Zhu J, Mburu M, Feroze R, Whitehurst DA, Lavery L, Cyriac J, Villanueva FS. Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function. Theranostics. 2019 Sep 21;9(23):7088-7098. eCollection 2019.

Kumar A, Noda K, Philips B, Velayuth-am M, Stolz DB, Gladwin MT, Shiva S, D’Cunha J. Nitrite attenuates mitochondrial impairment and vascular permeability induced by ischemia-reperfusion injury in the lung. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L580-L591. Epub 2020 Feb 19.

Li H, Sun H, Qian B, Feng W, Carney D, Miller J, Hogan MV, Wang L. Increased Expression of FGF-21 Negatively Affects Bone Homeostasis in Dystrophin/Utrophin Double Knockout Mice. J Bone Miner Res. 2020 Apr;35(4):738-752. Epub 2019 Dec 30.

Li X, Kim SE, Chen TY, Wang J, Yang X, Tabib T, Tan J, Guo B, Fung S, Zhao J, Sembrat J, Rojas M, Shiva S, Lafyatis R, St Croix C, Alder JK, Di YP, Kass DJ, Zhang Y. Toll interacting protein protects bronchial epithelial cells from bleomycin-induced apoptosis. FASEB J. 2020 Jun 28. Online ahead of print.

Liu HJ, Lam HC, Baglini CV, Nijmeh J, Cottrill AA, Chan SY, Henske EP. Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ). Oncogene. 2019 Dec;38(49):7367-7383. Epub 2019 Aug 16.

Liu M, Gomez D. Smooth Muscle Cell Phenotypic Diversity. Arterioscler Thromb Vasc Biol. 2019 Sep;39(9):1715-1723. Epub 2019 Jul 25.

Liu R, Jagannathan R, Sun L, Li F, Yang P, Lee J, Negi V, Perez-Garcia EM, Shiva S, Yechoor VK, Moulik M. Tead1 is essential for mitochondrial function in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H89-H99. Epub 2020 Jun 5.

Makani J, Sangeda RZ, Nnodu O, Nembaware V, Osei-Akoto A, Paintsil V, Balandya E, Kent J, Luzzatto L, Ofori-Acquah S, Olopade OI, Pallangyo K, Minja IK, Jonas M, Mazandu GK, Mulder N, Ohene-Frempong K, Wonkam A. SickleInAfrica. Lancet Haematol. 2020 Feb;7(2):e98-e99.

Mallampalli RK, Li X, Jang JH, Kaminski T, Hoji A, Coon T, Chandra D, Welty S, Teng Y, Sembrat J, Rojas M, Zhao Y, Lafyatis R, Zou C, Sciurba F, Sundd P, Lan L, Nyunoya T. Cigarette smoke exposure enhances transforming acidic coiled-coil-containing protein 2 turnover and thereby promotes emphysema. JCI Insight. 2020 Jan 30;5(2):e125895.

Maron BA, Gladwin MT, Bonnet S, De Jesus Perez V, Perman SM, Yu PB, Ichinose F. Perspectives on Cardiopulmonary Critical Care for Patients With COVID-19: From Members of the American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. J Am Heart Assoc. 2020 Jul 21;9(14):e017111. Epub 2020 Jun 18.

McCormick M, Richardson T, Warady BA, Novelli EM, Kalpatthi R. Acute kidney injury in paediatric patients with sickle cell disease is associated with increased morbidity and resource utilization. Br J Haematol. 2020 May;189(3):559-565. Epub 2020 Feb 6.

Moorhead WJ 3rd, Chu CC, Cuevas RA, Callahan J 4th, Wong R, Regan C, Boufford CK, Sur S, Liu M, Gomez D, MacTaggart JN, Kamenskiy A, Boehm M, St Hilaire C. Dysregulation of FOXO1 (Forkhead Box O1 Protein) Drives Calcification in Arterial Calcification due to Deficiency of CD73 and Is Present in Peripheral Artery Disease. Arterioscler Thromb Vasc Biol. 2020 Jul;40(7):1680-1694. Epub 2020 May 7.

Morris CR, Brown LAS, Reynolds M, Dampier CD, Lane PA, Watt A, Kumari P, Harris F, Manoranjithan S, Mendis RD, Figueroa J, Shiva S. Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain. Blood. 2020 Sep 17;136(12):1402-1406.

Musicki B, Anele UA, Campbell JD, Karakus S, Shiva S, Silva FH, Burnett AL. Dysregulated NO/PDE5 signaling in the sickle cell mouse lower urinary tract: Reversal by oral nitrate therapy. Life Sci. 2019 Dec 1;238:116922. Epub 2019 Oct 18.

Naeem MM, Maheshan R, Costford SR, Wahedi A, Trajkovski M, Plavec J, Yatsunyk LA, Ciesielski GL, Kaufman BA, Sondheimer N. G-quadruplex-mediated reduction of a pathogenic mitochondrial heteroplasmy. Hum Mol Genet. 2019 Oct 1;28(19):3163-3174.

Nguyen QL, Wang Y, Helbling N, Simon MA, Shiva S. Alterations in platelet bioenergetics in Group 2 PH-HF-pEF patients. PLoS One. 2019 Jul 31;14(7):e0220490. eCollection 2019.

Nouraie M, Darbari DS, Rana S, Minniti CP, Castro OL, Luchtman-Jones L, Sable C, Dham N, Kato GJ, Gladwin MT, Ensing G, Arteta M, Campbell A, Taylor JG 6th, Nekhai S, Gordeuk VR. Tricuspid regurgitation velocity and other biomarkers of mortality in children, adolescents and young adults with sickle cell disease in the United States: The PUSH study. Am J Hematol. 2020 Jul;95(7):766-774. Epub 2020 Apr 21.

Nouraie M, Little JA, Hildesheim M, Gibbs JSR, Morris CR, Machado RF, Kato GJ, Gordeuk VR, Gladwin MT. Validation of a composite vascular high-risk profile for adult patients with sickle cell disease. Am J Hematol. 2019 Dec;94(12):E312-E314. Epub 2019 Sep 17.

Novelli EM. COVID-19 and SCA: an old friend comes to the rescue. Blood. 2020 May 28;135(22):1925-1926.

Ofori-Acquah SF, Hazra R, Orikogbo OO, Crosby D, Flage B, Ackah EB, Lenhart D, Tan RJ, Vitturi DA, Paintsil V, Owusu-Dabo E, Ghosh S; SickleGenAfrica Network. Hemopexin deficiency promotes acute kidney injury in sickle cell disease. Blood. 2020 Mar 26;135(13):1044-1048.

Ofori-Acquah SF. Sickle cell disease as a vascular disorder. Expert Rev Hematol. 2020 Jun;13(6):645-653. Epub 2020 May 3.

Perkins LA, Anderson CJ, Novelli EM. Targeting P-Selectin Adhesion Molecule in Molecular Imaging: P-Selectin Expression as a Valuable Imaging Biomarker of Inflammation in Cardiovascular Disease. J Nucl Med. 2019 Dec;60(12):1691-1697. Epub 2019 Oct 10.

Pi H, Kosanovich CM, Handen A, Tao M, Visina J, Vanspeybroeck G, Simon MA, Risbano MG, Desai A, Mathier MA, Rivera-Lebron BN, Nguyen Q, Kliner J, Nouraie M, Chan SY. Outcomes of Pulmonary Arterial Hypertension Are Improved in a Specialty Care Center. Chest. 2020 Jul;158(1):330-340. Epub 2020 Feb 25.

Pradhan-Sundd T, Kosar K, Saggi H, Zhang R, Vats R, Cornuet P, Green S, Singh S, Zeng G, Sundd P, Nejak-Bowen K. Wnt/β-Catenin Signaling Plays a Protective Role in the Mdr2 Knockout Murine Model of Cholestatic Liver Disease. Hepatology. 2020 May;71(5):1732-1749. Epub 2019 Dec 31.

Pradhan-Sundd T. Sirtuin-6 in Hepatic Fibrosis: Does Cell Type Matter?. Cell Mol Gastroen-terol Hepatol. 2020;10(2):420-421. Epub 2020 May 29.

Qi X, Shen M, Fan P, Guo X, Wang T, Feng N, Zhang M, Sweet RA, Kirisci L, Wang L. The Performance of Gene Expression Signature-Guided Drug-Disease Association in Different Categories of Drugs and Diseases. Molecules. 2020 Jun 16;25(12):2776.

Qian W, Kumar N, Roginskaya V, Fouquerel E, Opresko PL, Shiva S, Watkins SC, Kolodieznyi D, Bruchez MP, Van Houten B. Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18435-18444. Epub 2019 Aug 26.

Rafikova O, Al Ghouleh I, Rafikov R. Focus on Early Events: Pathogenesis of Pulmonary Arterial Hypertension Development. Antioxid Redox Signal. 2019 Nov 1;31(13):933-953. Epub 2019 Jul 2.

Rochon ER, Corti P. Globins and nitric oxide homeostasis in fish embryonic development. Mar Genomics. 2020 Feb;49:100721. Epub 2019 Nov 8.

Rochon ER, Krowka MJ, Bartolome S, Heresi GA, Bull T, Roberts K, Hemnes A, Forde KA, Krok KL, Patel M, Lin G, McNeil M, Al-Naamani N, Roman BL, Yu PB, Fallon MB, Gladwin MT, Kawut SM. BMP9/10 in Pulmonary Vascular Complications of Liver Disease. Am J Respir Crit Care Med. 2020 Jun 15;201(12):1575-1578.

Rochon ER, Missinato MA, Xue J, Tejero J, Tsang M, Gladwin MT, Corti P. Nitrite Improves Heart Regeneration in Zebrafish. Antioxid Redox Signal. 2020 Feb 20;32(6):363-377. Epub 2019 Dec 12.

Rose JJ, Bocian KA, Xu Q, Wang L, DeMartino AW, Chen X, Corey CG, Guimarães DA, Azarov I, Huang XN, Tong Q, Guo L, Nouraie M, McTiernan CF, O’Donnell CP, Tejero J, Shiva S, Gladwin MT. A neuroglobin-based high-affinity ligand trap reverses carbon monoxide-induced mitochondrial poisoning. J Biol Chem. 2020 May 8;295(19):6357-6371. Epub 2020 Mar 23.

Rutledge C, Cater G, McMahon B, Guo L, Nouraie SM, Wu Y, Villanueva F, Kaufman BA. Commercial 4-dimensional echocardiography for murine heart volumetric evaluation after myocardial infarction. Cardiovasc Ultrasound. 2020 Mar 12;18(1):9.

Saygin D, Tabib T, Bittar HET, Valenzi E, Sembrat J, Chan SY, Rojas M, Lafyatis R. Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension. Pulm Circ. 2020 Feb 28;10(1). eCollection 2020 Jan-Mar.

Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB. Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. Circulation. 2020 Mar 24;141(12):1001-1026. Epub 2020 Mar 23.

Shen Y, Goncharov DA, Avolio T, Ray A, Okorie E, DeLisser H, Mora AL, Vanderpool R, Kudryashova TV, Goncharova EA. Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats. Pulm Circ. 2020 Feb 12;10(1):2045894019898593. eCollection 2020 Jan-Mar.

Singh KB, Hahm ER, Alumkal JJ, Foley LM, Hitchens TK, Shiva SS, Parikh RA, Jacobs BL, Singh SV. Reversal of the Warburg phenomenon in chemo-prevention of prostate cancer by sulforaphane. Carcinogenesis. 2019 Dec 31;40(12):1545-1556.

Song GJ, Gupta DP, Rahman MH, Park HT, Al Ghouleh I, Bisello A, Lee MG, Park JY, Park HH, Jun JH, Chung KW, Choi BO, Suk K. Loss-of-function of EBP50 is a new cause of hereditary peripheral neuropathy: EBP50 functions in peripheral nerve system. Glia. 2020 Sep;68(9):1794-1809. Epub 2020 Feb 20.

Sparkenbaugh EM, Chen C, Brzoska T, Nguyen J, Wang S, Vercellotti GM, Key NS, Sundd P, Belcher JD, Pawlinski R. Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease. Blood. 2020 May 14;135(20):1783-1787.

Spiekerkoetter E, Goncharova EA, Guignabert C, Stenmark K, Kwapiszewska G, Rabinovitch M, Voelkel N, Bogaard HJ, Graham B, Pullamsetti SS, Kuebler WM. Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure. Pulm Circ. 2019 Nov 20;9(4):2045894019889775. eCollection 2019 Oct-Dec.

St Hilaire C. Retinoids: Dissolving the Calcification Paradox. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):503-505. Epub 2020 Feb 26.

Stoner MW, McTiernan CF, Scott I, Manning JR. Calreticulin expression in human cardiac myocytes induces ER stress-associated apoptosis. Physiol Rep. 2020 Apr;8(8):e14400.

Tejero J. Negative surface charges in neuroglobin modulate the interaction with cytochrome c. Biochem Biophys Res Commun. 2020 Mar 12;523(3):567-572. Epub 2020 Jan 11.

Thapa D, Manning JR, Stoner MW, Zhang M, Xie B, Scott I. Cardiomyocyte-specific deletion of GCN5L1 in mice restricts mitochondrial protein hyperacetylation in response to a high fat diet. Sci Rep. 2020 Jun 30;10(1):10665.

Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW II, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, O’Brien KD, O’Rourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L. Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop. Circulation. 2019 Oct 1;140(14):1205-1216.

Triantafyllou GA, Tiberio PJ, Zou RH, Lamberty PE, Lynch MJ, Kreit JW, Gladwin MT, Morris A, Chiarchiaro J. Vaping-associated Acute Lung Injury: A Case Series. Am J Respir Crit Care Med. 2019 Dec 1;200(11):1430-1431.

Trumpff C, Marsland AL, Basual-to-Alarcón C, Martin JL, Carroll JE, Sturm G, Vincent AE, Mosharov EV, Gu Z, Kaufman BA, Picard M. Acute psychological stress increases serum circulating cell-free mitochondrial DNA. Psychoneuroendocrinology. 2019 Aug;106:268-276. Epub 2019 Mar 28.

Trumpff C, Marsland AL, Sloan RP, Kaufman BA, Picard M. Predictors of ccf-mtDNA reactivity to acute psychological stress identified using machine learning classifiers: A proof-of-concept. Psychoneuroendocrinology. 2019 Sep;107:82-92. Epub 2019 May 7.

Vara D, Cifuentes-Pagano E, Pagano PJ, Pula G. A novel combinatorial tech-nique for simultaneous quantification of oxygen radicals and aggregation reveals unexpected redox patterns in the activation of platelets by different physiopathological stimuli. Haema-tologica. 2019 Sep;104(9):1879-1891. Epub 2019 Jan 24.

Vats R, Brzoska T, Bennewitz MF, Jimenez MA, Pradhan-Sundd T, Tutuncuoglu E, Jonassaint J, Gutierrez E, Watkins SC, Shiva S, Scott MJ, Morelli AE, Neal MD, Kato GJ, Gladwin MT, Sundd P. Platelet Extracellular Vesicles Drive Inflammasome-IL-1β-Depen-dent Lung Injury in Sickle Cell Disease. Am J Respir Crit Care Med. 2020 Jan 1;201(1):33-46.

Vats R, Liu S, Zhu J, Mukhi D, Tutuncuoglu E, Cardenes N, Singh S, Brzoska T, Kosar K, Bamne M, Jonassaint J, Adebayo Michael A, Watkins SC, Hillery C, Ma X, Nejak-Bowen K, Rojas M, Gladwin MT, Kato GJ, Ramakrishnan S, Sundd P, Monga SP, Pradhan-Sundd T. Impaired bile secretion promotes hepatobiliary injury in Sickle Cell Disease. Hepatology. 2020 Mar 19. Online ahead of print.

Vats R, Tutuncuoglu E, Pradhan-Sundd T, Tejero J, Shaw GD, Sundd P. Tandem P-selectin glycoprotein ligand immunoglobulin prevents lung vaso-occlusion in sickle cell disease mice. Exp Hematol. 2020 Apr;84:1-6.e1. Epub 2020 Mar 31.

Vitturi DA, Maynard C, Olsufka M, Straub AC, Krehel N, Kudenchuk PJ, Nichol G, Sayre M, Kim F, Dezfulian C. Nitrite elicits divergent NO-dependent signaling that associates with outcome in out of hospital cardiac arrest. Redox Biol. 2020 May;32:101463. Epub 2020 Feb 14.

Wang L, Halliday G, Huot JR, Satoh T, Baust JJ, Fisher A, Cook T, Hu J, Avolio T, Goncharov DA, Bai Y, Vanderpool RR, Considine RV, Bonetto A, Tan J, Bachman TN, Sebastiani A, McTiernan CF, Mora AL, Machado RF, Goncharova EA, Gladwin MT, Lai YC. Treatment With Treprostinil and Metformin Normalizes Hyperglycemia and Improves Cardiac Function in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):1543-1558. Epub 2020 Apr 9.

Wang L, Sparacino-Watkins CE, Wang J, Wajih N, Varano P, Xu Q, Cecco E, Tejero J, Soleimani M, Kim-Shapiro DB, Gladwin MT. Carbonic anhydrase II does not regulate nitrite-dependent nitric oxide formation and vasodilation. Br J Pharmacol. 2020 Feb;177(4):898-911. Epub 2019 Dec 23.

Winnica D, Corey C, Mullett S, Reynolds M, Hill G, Wendell S, Que L, Holguin F, Shiva S. Bioenergetic Differences in the Airway Epithelium of Lean Versus Obese Asthmatics Are Driven by Nitric Oxide and Reflected in Circulating Platelets. Antioxid Redox Signal. 2019 Oct 1;31(10):673-686. Epub 2019 Mar 6.

Wood KC, Durgin BG, Schmidt HM, Hahn SA, Baust JJ, Bachman T, Vitturi DA, Ghosh S, Ofori-Acquah SF, Mora AL, Gladwin MT, Straub AC. Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice. Blood Adv. 2019 Dec 10;3(23):4104-4116.

Wood KC, Gladwin MT, Straub AC. Sickle cell disease: at the crossroads of pulmonary hypertension and diastolic heart failure. Heart. 2020 Apr;106(8):562-568. Epub 2019 Dec 10.

Woodcock CC, Chan SY. The Search for Disease-Modifying Therapies in Pulmonary Hypertension. J Cardiovasc Pharmacol Ther. 2019 Jul;24(4):334-354. Epub 2019 Feb 17.

Wu K, Scott I, Wang L, Thapa D, Sack MN. The emerging roles of GCN5L1 in mitochondrial and vacuolar organelle biology. Biochim Biophys Acta Gene Regul Mech. 2020 Jun 26:194598. Online ahead of print.

Yazdani HO, Roy E, Comerci AJ, van der Windt DJ, Zhang H, Huang H, Loughran P, Shiva S, Geller DA, Bartlett DL, Tsung A, Sheng T, Simmons RL, Tohme S. Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth. Cancer Res. 2019 Nov 1;79(21):5626-5639. Epub 2019 Sep 13.

Yu GZ, Istvanic F, Chen X, Nouraie M, Shiva S, Straub AC, Pacella JJ. Ultrasound-Targeted Microbubble Cavitation with Sodium Nitrite Synergistically Enhances Nitric Oxide Production and Microvascular Perfusion. Ultrasound Med Biol. 2020 Mar;46(3):667-678. Epub 2019 Dec 3.

Zhang X, Shah BN, Zhang W, Saraf SL, Nouraie M, Nekhai S, Machado RF, Gladwin MT, Gordeuk VR. S100B has pleiotropic effects on vaso-occlusive manifestations in sickle cell disease. Am J Hematol. 2020 Mar;95(3):E62-E65. Epub 2020 Jan 1.

Zhao J, Florentin J, Tai YY, Torrino S, Ohayon L, Brzoska T, Tang Y, Yang J, Negi V, Woodcock CC, Risbano MG, Nouraie SM, Sundd P, Bertero T, Dutta P, Chan SY. Long Range Endocrine Delivery of Circulating miR-210 to Endothelium Promotes Pulmonary Hypertension. Circ Res. 2020 Aug 14;127(5):677-692. Epub 2020 Jun 4.

Zou RH, Tiberio PJ, Triantafyllou GA, Lamberty PE, Lynch MJ, Kreit JW, McVerry BJ, Gladwin MT, Morris A, Chiarchiaro J, Fitzpatrick ME, Rose JJ. Clinical Characterization of E-Cigarette, or Vaping, Product Use-associated Lung Injury in 36 Patients in Pittsburgh, Pennsylvania. Am J Respir Crit Care Med. 2020 May 15;201(10):1303-1306.

Zou RH, Wallace WD, Nouraie SM, Chan SY, Risbano MG. Lower DLco% identifies exercise pulmonary hypertension in patients with parenchymal lung disease referred for dyspnea. Pulm Circ. 2020 Feb 19;10(1):2045894019891912. eCollection 2020 Jan-Mar.