Bing Wang, MD, PhD

Phone: 412-383-6955

Associate Professor of Medicine, Division of Cardiology
Director, AAV Gene Therapy Core

Bio

Dr. Wang received his MD from Tong-Ji Medical School, Huazhong University of Science and Technology. After receiving his medical degree, he studied at the Institute of Microbiology, Chinese Academy of Sciences in Beijing, where he earned his PhD in Molecular Biology and Virology. Dr. Wang then held a position as an Associate Professor at the Chinese Academy of Sciences in China while simultaneously working a post-doctoral fellowship at the University of Science and Technology in Hong Kong. He also spent time as the Physician-in-Charge at Institute of Geriatrics, Tong-Ji Medical School in Wuhan.

When Dr. Wang joined the University of Pittsburgh in 1999, he was a Research Associate in the Department of Molecular Genetics and Biochemistry and was subsequently promoted to Assistant Professor and Associate Professor in the Department of Orthopaedic Surgery (2006-2022). Shortly before becoming a faculty member at the University of Pittsburgh, Dr. Wang was awarded two, 2-year postdoctoral scholarships. The first scholarship was from the Duchenne Muscular Dystrophy Research Center and the second was from the Center for Cell Therapeutics. He has also repeatedly won the Orthopaedic Research Society’s New Investigator Recognition Award (2007, 2011) and also won the North American Spine Society and the Spine Journal’s 2011 Outstanding Paper Award (Basic Science).

Research Interests

Dr. Wang’s current research interest is focused on gene and cell therapies combined with bioengineering for muscle diseases and regenerative medicine, especially for the viral vector-mediated in vivo gene replacement and anti-inflammation to treat genetic musculoskeletal diseases such as Duchenne muscular dystrophy (DMD). He has a long history of working on gene- and cell-based therapies for musculoskeletal injuries and diseases (heart and lung), mainly by using recombinant adeno-associated viral (rAAV) vectors, and have extensive, published expertise and technology to develop these vectors for the basic and translational researches. He is also actively engaged in multiple applications of different viral vectors for gene and cell therapies, such as the ex vivo gene transfer-based genetic modification of stem cell and gene-activated bio-scaffold for hard and soft tissue healing. Dr. Wang’s current research interests include:

Gene replacement and anti-inflammation for the treatment of neuromuscular genetic disease
Gene therapy for the treatment of heart, lung, and blood disorders
Vascular–targeted gene therapy for tissue regeneration
Gene- and cell-activated 3D bioscaffolds for tissue regeneration and repair
Development of gene delivery system for in vivo and ex vivo gene therapy

Education and Training

MD, Tong-Ji Medical School, Huazhong University of Science and Technology, Wuhan, China, 1986
PhD in Molecular Biology & Virology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China, 1998

Internship, Tong-Ji Medical School, Huazhong University of Science and Technology, Wuhan, China, 1986
Resident Physician in Internal Medicine, Institute of Geriatrics, Tong-Ji Medical School, Huazhong University of Science and Technology, Wuhan, China, 1991
Post-Doctoral Researcher, Dept. of Biochemistry, Hong Kong University of Science and Technology, Hong Kong, China, 1999

Selected/Representative Publications

For a complete bibliography, click here.