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VMI
 


Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Bullock Laboratory

Contact

Lab phone: 412-624-7672

Lab address: E1200 Biomedical Science Tower (Starzl BST), 200 Lothrop Street, Pittsburgh, PA 15261

 

Research

The Bullock Lab is interested in disorders of blood cell production and function in human hematologic diseases with a major focus on the influence of iron deficiency/sequestration on erythropoiesis in a variety of anemias. A related area of interest is the role of mitochondrial metabolism in erythropoiesis and megakaryopoiesis. We are also involved in several collaborative studies. Collaborative projects include: Investigating the role of specific erythrocyte membrane proteins in the regulation of cell shape, stability and life-span during sickle cell disease and red blood cell storage; investigating the role of intraerythrocyte IL33 in hemolytic anemias; investigating the role of NRF2 in iron deficiency anemia and stress erythropoiesis; investigating the role of guanyl cyclase in fetal hemoglobin induction; investigating the role of HMGB1 in megakaryopoiesis; and investigating the role of sex hormones in erythropoiesis. The primary long-term goals of the laboratory are to understand how intrinsic and extrinsic factors regulate red blood cell production and survival in patients with anemia and use this knowledge to improve therapy for these patients.

People

PRINCIPAL INVESTIGATOR
  Bullock

GRANT C. BULLOCK, MD, PhD

Assistant Professor of Pathology, DIvision of Hematopathology

bullockgc@upmc.edu | 412-624-7523

 

GRADUATE STUDENTS
  naomi gunawardena

NAOMI GUNAWARDENA

Student, Physician Scientist Training Program

ndg14@pitt.edu | 412-624-7672

 

RESEARCH STAFF
  Val Schrott

VALERIE SCHROTT, MS

Research III

vas59@pitt.edu | 412-624-7672

 

Previous Lab Members

Chanté Richardson, PhD, Postdoctoral Scholar 2014-2015, Current Position: Assistant Professor of Biochemistry, Alabama College of Osteopathic Medicine